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{
"id": "ibiosim",
"name": "iBioSim",
"version": "3.1.0",
"description": "iBioSim is a computer-aided design (CAD) tool aimed for the modeling, analysis, and design of genetic circuits. While iBioSim primarily targets models of genetic circuits, models representing metabolic networks, cell-signaling pathways, and other biological and chemical systems can also be analyzed.",
"url": "https://github.com/MyersResearchGroup/iBioSim",
"image": "docker.io/paytonco/ibiosim:latest",
"format": {
"namespace": "EDAM",
"id": "format_3973"
},
"authors": [{
"firstName": "Chris",
"middleName": "J.",
"lastName": "Myers"
},
{
"firstName": "Leandro",
"middleName": null,
"lastName": "Watanabe"
},
{
"firstName": "Tramy",
"middleName": null,
"lastName": "Nguyen"
},
{
"firstName": "Pedro",
"middleName": null,
"lastName": "Fontanarosa"
},
{
"firstName": "Michael",
"middleName": null,
"lastName": "Zhang"
},
{
"firstName": "Zach",
"middleName": null,
"lastName": "Zundel"
},
{
"firstName": "Mihai",
"middleName": null,
"lastName": "Glont"
},
{
"firstName": "Nathan",
"middleName": null,
"lastName": "Barker"
},
{
"firstName": "Scott",
"middleName": null,
"lastName": "Glass"
},
{
"firstName": "Kevin",
"middleName": null,
"lastName": "Jones"
},
{
"firstName": "Hiroyuki",
"middleName": null,
"lastName": "Kuwahara"
},
{
"firstName": "Curtis",
"middleName": null,
"lastName": "Madsen"
},
{
"firstName": "Nam",
"middleName": null,
"lastName": "Nguyen"
},
{
"firstName": "Tyler",
"middleName": null,
"lastName": "Patterson"
},
{
"firstName": "Nicholas",
"middleName": null,
"lastName": "Roehner"
},
{
"firstName": "Jason",
"middleName": null,
"lastName": "Stevens"
},
{
"firstName": "Payton",
"middleName": "J.",
"lastName": "Thomas"
},
{
"firstName": "Zhen",
"middleName": null,
"lastName": "Zhang"
}
],
"references": {
"identifiers": [],
"citations": [{
"title": "Design and test of genetic circuits using iBioSim",
"authors": "Curtis Madsen, Chris J. Myers, Tyler Patterson, Nicholas Roehner, Jason T. Stevens & Chris Winstead",
"journal": "IEEE Design Test of Computers",
"volume": 29,
"pages": "32-39",
"year": 2012,
"identifiers": [{
"namespace": "doi",
"id": "10.1109/MDT.2012.2187875",
"url": "https://doi.org/10.1109/MDT.2012.2187875"
}]
},
{
"title": "Dynamic modeling of cellular populations within iBioSim",
"authors": "Jason T. Stevens & Chris J. Myers",
"journal": "ACS Synthetic Biology",
"volume": 2,
"pages": "223-229",
"year": 2013,
"identifiers": [{
"namespace": "doi",
"id": "10.1021/sb300082b",
"url": "https://doi.org/10.1021/sb300082b"
}]
},
{
"title": "iBioSim: a tool for the analysis and design of genetic circuits",
"authors": "Chris J. Myers, Nathan Barker, Kevin Jones, Hiroyuki Kuwahara, Curtis Madsen & Nam-Phuong D. Nguyen",
"journal": "Bioinformatics",
"volume": 25,
"pages": "2848-2849",
"year": 2009,
"identifiers": [{
"namespace": "doi",
"id": "10.1093/bioinformatics/btp457",
"url": "https://doi.org/10.1093/bioinformatics/btp457"
}]
},
{
"title": "iBioSim 3: a tool for model-based genetic circuit design",
"authors": "Leandro Watanabe, Tramy Nguyen, Michael Zhang, Zach Zundel, Zhen Zhang, Curtis Madsen, Nicholas Roehner & Chris J. Myers",
"journal": "ACS Synthetic Biology",
"volume": 8,
"pages": "1560-1563",
"year": 2019,
"identifiers": [{
"namespace": "doi",
"id": "10.1021/acssynbio.8b00078",
"url": "https://doi.org/10.1021/acssynbio.8b00078"
}]
}
]
},
"license": {
"namespace": "SPDX",
"id": "Apache-2.0"
},
"algorithms": [{
"id": "hode",
"name": "Runge-Kutta-Fehlberg (Hierarchical)",
"kisaoId": {
"namespace": "KISAO",
"id": "KISAO_0000086"
},
"modelingFrameworks": [{
"namespace": "SBO",
"id": "SBO_0000293"
}],
"modelFormats": [{
"namespace": "EDAM",
"id": "format_2585"
}],
"simulationFormats": [{
"namespace": "EDAM",
"id": "format_3685"
}],
"archiveFormats": [{
"namespace": "EDAM",
"id": "format_3686"
}],
"citations": [{
"title": "Low-order classical Runge-Kutta formulas with stepsize control and their application to some heat transfer problems",
"authors": "Erwin Fehlberg",
"journal": "NASA Technical Report",
"pages": "1-49",
"year": 1969,
"identifiers": [{
"namespace": "NTRS",
"id": "NASA-TR-R-315",
"url": "https://ntrs.nasa.gov/citations/19690021375"
}]
}],
"parameters": [{
"kisaoId": {
"namespace": "KISAO",
"id": "KISAO_0000209"
},
"id": "rel_tol",
"name": "Relative tolerance",
"type": "float",
"value": 0.000001
}]
}],
"biosimulators": {
"schemaVersion": "1.0.0",
"imageVersion": "1.0.0"
},
"created": "2020-01-01T12:00:00Z",
"updated": "2020-01-01T12:00:00Z"
}