Lukas AlphaFold Guide

→ Read the live guide

A practical, beginner-to-expert guide to AlphaFold2, ColabFold, AlphaFold3, AlphaMissense, and hands-on structure analysis in ChimeraX.

Run it locally

Prefer your own copy over the live site? You need Python 3.9+.

1. Get the files — either:

git clone https://github.com/LUKASinScience/AlphaFold-Guide.git

or on this page: Code → Download ZIP, then unzip it. No git required either way.

2. Install Zensical (the static site generator this guide is built with):

cd AlphaFold-Guide
python -m venv .venv && source .venv/bin/activate
pip install zensical

3. Run it:

zensical serve

Open the printed http://localhost:8000 address — live-reloading, full search, identical to the hosted site.

Warning

If you use zensical build instead (produces a static site/ folder), don't just double-click the resulting index.html — opening it directly (file://) silently breaks the search box. Serve that folder too, e.g. python -m http.server from inside site/ (no extra install needed), then open http://localhost:8000.

docs/ holds all content; zensical.toml holds config and nav.

License

CC BY 4.0 — see LICENSE and THIRD_PARTY_NOTICES.md (vendored Mol* viewer is MIT).

Author

Lukas W. Bauer — github.com/LUKASinScience · plugins used by this guide: ChopChopMF, ChimeraX-FigureStyle