Step 1: Dataset Creation Patients dataset: run directly code in dataset_building folder (instructions in the README file) Carriers dataset: identify BRCA carriers (carriers_identification folder), build carriers dataset based on them (dataset_building folder) Step 2: Model Training model_training folder, instructions in the README file Step 3: Performace Plots Generation Summary plots and boxplots about model performace are in the generate_plots.ipynb file Step 4: Interpretation ACMG annotation and classification + GISs distribution plots + ECDF plots for ACMG and GISs based scoring in the interpretation folder