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HLA Modeller

This script builds three-dimensional models of the most common and well-documented HLA alleles. Sequences are taken from the latest IPD-IMGT/HLA release and folded with Meta's ESMFold via the ESM Atlas API.

Instructions

Structures are at the output folder. To regenerate models after an IPD-IMGT/HLA release, run bundle install && ruby run.rb. To view a model, download its PDB file from output and open it in a viewer such as Mol*.

Support

You can contact me at: mariomarroquim@gmail.com.

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Generate 3D models of HLA alleles via Meta's ESMFold

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